Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 3/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491455 | 0.81 | FAAH (0.48) | FAAHMGLLNPC1TSHRRAB9A | |
| SCHEMBL2494284 | 0.79 | ELANE (0.45) | KMT2AFAAHMGLLNPC1TSHR | |
| SCHEMBL2490792 | 0.72 | POLB (0.45) | KMT2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL31301176 | 0.69 | MAPT (0.50) | KMT2ATSHRRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3343039 | 0.69 | POLB (0.52) | KMT2ANPC1TSHRRAB9AL3MBTL1 | |
| SCHEMBL5331706 | 0.69 | FAAH (0.65) | FAAHMGLLNPC1TSHRRAB9A | |
| SCHEMBL11165792 | 0.66 | SMN1; SMN2 (0.40) | KMT2AL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3716873 | 0.66 | SRC (0.38) | KMT2ANPC1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7217441 | 0.65 | MAOA (0.44) | KMT2ATSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12604032 | 0.65 | IDO1 (0.52) | KMT2AL3MBTL1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278741-A1 | MUSCARINIC AGONISTS | Acadia Pharmaceuticals Inc. (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001083472-A1 | MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2001-11-08 | — | — | WO | disclosed |