Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 8/20 | 0.41 |
| ▸ | ADH1C | P00326 | 6/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ADH4 | P08319 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 2/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748432 | 0.82 | ADH1A (0.38) | ADH1AADH1CADH4 | |
| SCHEMBL13082953 | 0.78 | ADH1A (0.42) | ADH1AADH1CALOX5 | |
| SCHEMBL11638870 | 0.75 | SLC6A2 (0.30) | ALOX5 | |
| SCHEMBL18602764 | 0.73 | ADH1C (0.35) | ADH1AADH1CALOX5 | |
| SCHEMBL24754603 | 0.69 | ADH1A (0.36) | ADH1AADH1CADH4 | |
| SCHEMBL29957210 | 0.69 | ADH1A (0.55) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL11903812 | 0.68 | ADH1A (0.41) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL11903729 | 0.68 | ADH1B (0.41) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL23425524 | 0.67 | TMEM97 (0.37) | ADH1AADH1C | |
| SCHEMBL613463 | 0.66 | ADH1A (0.50) | ADH1AADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9468632-B2 | Methods and compositions for targeting cancer stem cells | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-18 | — | — | US | disclosed |