Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.56 |
| ▸ | SHBG | P04278 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.52 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638959 | 1.00 | NR3C1 (0.68) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| SCHEMBL4546 | 0.82 | NR3C1 (0.74) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| SCHEMBL143178 | 0.82 | NR3C1 (0.74) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| SCHEMBL11156788 | 0.81 | ALDH1A1 (0.71) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| SCHEMBL11156797 | 0.81 | ALDH1A1 (0.71) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| Fludrocortisone SCHEMBL23975175 | 0.81 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| Fludrocortisone SCHEMBL14373312 | 0.81 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| Fludrocortisone SCHEMBL4545 | 0.81 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| Fludrocortisone SCHEMBL10598529 | 0.81 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 | |
| Fludrocortisone SCHEMBL13026141 | 0.81 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127589-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |