Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63728 | 0.84 | HSD11B1 (0.49) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL29732755 | 0.84 | HSD11B1 (0.49) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL11635736 | 0.83 | HSD11B1 (0.47) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL28949240 | 0.81 | LMNA (0.56) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL22507458 | 0.79 | BCHE (0.47) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL4622519 | 0.76 | HSD11B1 (0.41) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL18722090 | 0.76 | SMN1; SMN2 (0.48) | HSD11B1LMNARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL274962 | 0.75 | HSD11B1 (0.58) | HSD11B1CYP2A6SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL3246792 | 0.75 | BCHE (0.46) | HSD11B1CYP2A6LMNANPC1RAB9A | |
| SCHEMBL10071744 | 0.74 | BCHE (0.54) | HSD11B1SMN1; SMN2PTGS1PTGS2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4078934-A | Photosensitive, image-forming composition containing a leuco 2,3-disubstituted-1-indanone and a photooxidant | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-03-14 | — | — | US | disclosed |
| US-3992450-A | PHOTOSENSITIVE COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-16 | — | — | US | disclosed |