SCHEMBL274962

SCHEMBL274962

Cn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 9/20 0.58
CYP2A6 P11509 1/20 0.44
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PTGER1 P34995 1/20 0.42
FABP4 P15090 2/20 0.42
FABP5 Q01469 1/20 0.42
KMT2A Q03164 1/20 0.40
CRHR1 P34998 1/20 0.40
MAPK13 O15264 1/20 0.40
RAF1 P04049 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12680249 0.87 HSD11B1 (0.51) HSD11B1CYP2A6PTGS1PTGS2MAPT
SCHEMBL822678 0.81 PTGER1 (0.56) PTGER1FABP4FABP5MAPK13MAPK12
SCHEMBL8823116 0.81 HSD11B1 (0.54) HSD11B1CYP2A6PTGER1KMT2A
SCHEMBL63728 0.78 HSD11B1 (0.49) HSD11B1CYP2A6PTGS1PTGS2SMN1; SMN2
SCHEMBL29732755 0.78 HSD11B1 (0.49) HSD11B1CYP2A6PTGS1PTGS2SMN1; SMN2
SCHEMBL8823133 0.77 HSD11B1 (0.52) HSD11B1CYP2A6PTGS1PTGS2PTGER1
SCHEMBL27508406 0.76 HSD11B1 (0.49) HSD11B1CYP2A6PTGS1PTGS2MAPT
SCHEMBL11635736 0.76 HSD11B1 (0.47) HSD11B1CYP2A6PTGS1PTGS2SMN1; SMN2
SCHEMBL28949240 0.75 LMNA (0.56) HSD11B1CYP2A6PTGS1PTGS2SMN1; SMN2
SCHEMBL11640258 0.75 HSD11B1 (0.46) HSD11B1CYP2A6PTGS1PTGS2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361702-B2 Resin composition for laser engraving, resin printing plate precursor for laser engraving, relief printing plate and method for production of relief printing plate FUJIFILM CORPORATION (JP) 2013-01-29 US disclosed
US-20120082836-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD FOR PRODUCTION OF RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-8133654-B2 Laser-decomposable resin composition and laser-decomposable pattern-forming material and flexographic printing plate precursor of laser engraving type using the same FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-7872059-B2 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-7790348-B2 Decomposable resin composition and flexographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2010-09-07 US disclosed
US-7741010-B2 Polyester, polyurethane, polyether, polyamide, polyurea formed by a monomer containing two imine groups in the back bone and two end groups containing OH, NR2H, COOH, COCL, COOR, NCO and NCS group polymerized with other monomers; a photolatent or heat latent catalyst such as onium compounds, triazines FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-7718343-B2 Decomposable resin composition and pattern-forming material including the same FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090246653-A1 RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE, AND METHOD OF MANUFACTURING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-7582410-B2 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7435529-B2 Photosensitive composition and image recording method using the same FUJIFILM CORPORATION (JP) 2008-10-14 US disclosed
US-7422837-B2 Photosensitive composition FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-20080194762-A1 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080161476-A1 A binder polymer mixed with polysaccharide-modified carbon nanotubes or fullerenes and a monomer; efficient engraving with a low laser energy; improved recyclability FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080070154-A1 DECOMPOSABLE RESIN COMPOSITION AND PATTERN-FORMING MATERIAL INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
US-20080057437-A1 heat-decomposable cured polyurethane having an aromatic group is directly connected to a urethane bond; high sensitivity to easily form a pattern FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-20080038663-A1 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
US-7285374-B2 Light-sensitive lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-10-23 US disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070231737-A1 polymer having a carbon-carbon unsaturated bond in then chain and a side chain; butadiene-styrene copolymer; thick layer efficiently engraved with low laser energy; sensitivity FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed