Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027360 | 0.89 | LMNA (0.48) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL4929584 | 0.88 | MIF (0.44) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL5864432 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11650332 | 0.86 | SMN1; SMN2 (0.44) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL5664612 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11648025 | 0.85 | USP2 (0.42) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL9300423 | 0.84 | CYP17A1 (0.51) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| Water SCHEMBL11643609 | 0.83 | CYP17A1 (0.50) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11649700 | 0.81 | SENP1 (0.37) | MAPTRAB9APTPN11CYP17A1CA1 | |
| SCHEMBL11090977 | 0.79 | NAMPT (0.53) | MAPTKMT2AMEN1PTPN11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044047-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-23 | — | — | US | claimed |
| US-4111981-A | SUBSTITUTED PHENYLGLYCINES | SMITHKLINE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4107440-A | (CARBOALKOXYALKYLTHIO)-SUBSTITUTED PHENYLGLYCINES | SMITHKLINE CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4092480-A | Intermediates for preparing substituted phenylglycylcephalosporins | SMITHKLINE CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4044047-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |
| US-4022895-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4018921-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |
| US-4013764-A | PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED PHENYLGLYCYLCEPHALOSPORINS AND METHODS OF TREATING BACTERIAL INFECTIONS | SMITHKLINE CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3953439-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |