SCHEMBL11650552

SCHEMBL11650552

CCNc1[c]cccc1C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
RECQL P46063 1/20 0.33
ELANE P08246 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600275 0.78 TRPA1 (0.33)
SCHEMBL11655942 0.77 ALDH1A1 (0.33) MAPTHTTCYP3A4
SCHEMBL7264389 0.73 SMN1; SMN2 (0.38) MAPTHTT
SCHEMBL3761931 0.72 ALDH1A1 (0.45) MAPTHTTTSHR
SCHEMBL9468340 0.71 TDP1 (0.37) TSHRCYP3A4RECQLELANEACHE
SCHEMBL5249830 0.69 HPGD (0.43) MAPTHTTTSHRCYP3A4RECQL
SCHEMBL1505276 0.69 ALDH1A1 (0.35) TSHR
SCHEMBL258549 0.68 TSHR (0.32) TSHRACHE
SCHEMBL10766968 0.68 ALDH1A1 (0.50) MAPTHTTTSHRCYP3A4
SCHEMBL216731 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4120690-A 2-Acylaminothiazol-4-ylacetamides as post-emergent selective herbicides GULF OIL CORPORATION (US) 1978-10-17 US disclosed