SCHEMBL1165632

SCHEMBL1165632

O=C1CC(=O)N(Sc2ccccc2)C(=O)N1Sc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
ALDH1A1 P00352 6/20 0.44
HSD17B10 Q99714 3/20 0.44
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
GAA P10253 3/20 0.39
USP2 O75604 2/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.33
HPGD P15428 2/20 0.33
MGLL Q99685 2/20 0.33
CYP1A2 P05177 1/20 0.32
CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829977 0.79 MAPT (0.49) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL812586 0.78 MAPT (0.52) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8379436 0.77 MEN1 (0.42) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL20503175 0.73 ALDH1A1 (0.43) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL6709727 0.72 GSK3A (0.44) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1163597 0.71 MGLL (0.50) MAPTALDH1A1HSD17B10HTTSMN1; SMN2
SCHEMBL1041075 0.71 MAPT (0.41) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL30872008 0.70 CASP3 (0.48) MAPTALDH1A1HSD17B10NPC1RAB9A
SCHEMBL809458 0.70 CASP3 (0.48) MAPTALDH1A1HSD17B10NPC1RAB9A
SCHEMBL11286851 0.69 RAB9A (0.38) MAPTALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108959-B Photobleachable visible light initiator containing benzylidene ketone structure, and preparation method and application thereof 武汉大学 2023-05-16 CN disclosed
EP-2262050-B1 Photoelectric conversion element sensitized with methine dyes NIPPON KAYAKU KK (JP) 2013-09-04 EP disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
EP-2262050-A1 Photoelectric conversion element sensitized with methine dyes Nippon Kayaku Kabushiki Kaisha (JP) 2010-12-15 EP disclosed
US-7851701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2010-12-14 US disclosed
EP-2259378-A1 Photoelectric conversion element sensitized with methine dyes Nippon Kayaku Kabushiki Kaisha (JP) 2010-12-08 EP disclosed
US-20040187918-A1 Photoelectric conversion element sensitized with coloring matter NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2004-09-30 US disclosed
EP-1422782-A1 PHOTOELECTRIC CONVERSION ELEMENT SENSITIZED WITH COLORING MATTER Nippon Kayaku Kabushiki Kaisha (JP) 2004-05-26 EP disclosed
US-4389477-A Photoconductive composition sensitized by a thiobarbituric acid derivative FUJI PHOTO FILM CO., LTD. (JP) 1983-06-21 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed