Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661168 | 0.84 | MTNR1B (0.37) | MTNR1AMTNR1B | |
| SCHEMBL11657741 | 0.84 | RAB9A (0.54) | SMN1; SMN2RAB9AMAPTHPGDMTNR1A | |
| SCHEMBL11660879 | 0.81 | NPC1 (0.43) | SMN1; SMN2RAB9AACACBMAPTHPGD | |
| SCHEMBL11661228 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL11663684 | 0.80 | ACACB (0.36) | RAB9AACACBMAPTHPGDALDH1A1 | |
| SCHEMBL11658257 | 0.79 | NPC1 (0.50) | SMN1; SMN2RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL11663688 | 0.77 | MAPT (0.45) | RAB9AMAPTHPGDALDH1A1NPC1 | |
| SCHEMBL11661014 | 0.77 | PYCR1 (0.42) | SMN1; SMN2RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL11658712 | 0.76 | ACHE (0.41) | SMN1; SMN2RAB9AMAPTHPGDALDH1A1 | |
| SCHEMBL11665519 | 0.72 | ALDH1A1 (0.51) | ACACBMAPTHPGDALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075006-A | PESTICIDES, NEMATOCIDES, FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1978-02-21 | — | — | US | disclosed |