Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.39 |
| ▸ | HTR3B | O95264 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659464 | 0.85 | NR3C1 (0.43) | PNMTRIPK1NR3C1TAAR1HTR3E | |
| SCHEMBL11662934 | 0.80 | SLC6A2 (0.45) | TAAR1RECQLCYP3A4 | |
| SCHEMBL11659107 | 0.79 | HTR2A (0.45) | TAAR1IDO1MAOB | |
| SCHEMBL8324906 | 0.78 | MAOB (0.52) | PNMTRIPK1NR3C1TAAR1HTR3E | |
| SCHEMBL11667803 | 0.78 | RIPK1 (0.48) | PNMTRIPK1NR3C1TAAR1HTR3E | |
| SCHEMBL11613482 | 0.77 | TSHR (0.43) | PNMTRIPK1TAAR1HTR3EHTR3B | |
| SCHEMBL28477012 | 0.76 | PNMT (0.48) | PNMTRIPK1NR3C1TAAR1HTR3E | |
| SCHEMBL11659390 | 0.76 | HTR3E (0.44) | PNMTRIPK1NR3C1TAAR1HTR3E | |
| SCHEMBL11663860 | 0.75 | TAAR1 (0.46) | PNMTRIPK1TAAR1HTR3EHTR3B | |
| SCHEMBL73643 | 0.74 | PNMT (0.54) | PNMTRIPK1TAAR1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |