Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MYLK | Q15746 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CLPP | Q16740 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434587 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL116437 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL3434578 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPK1GAAMAPTKDM4E | |
| SCHEMBL116629 | 0.80 | LMNA (0.47) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL115542 | 0.79 | LMNA (0.50) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL167919 | 0.79 | LMNA (0.46) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL3524088 | 0.78 | LMNA (0.47) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL16104436 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPK1GAAMAPTRAB9A | |
| SCHEMBL115543 | 0.76 | AKT1 (0.51) | AKT1MYLKMAPK14C5AR1MEN1 | |
| SCHEMBL16104427 | 0.75 | C5AR1 (0.54) | ALDH1A1GAAMAPTKDM4EAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010125343-A1 | COMPOUNDS FOR INDUCING CELLULAR APOPTOSIS | QUEEN MARY AND WESTFIELD COLLEGE (GB) | 2010-11-04 | — | — | WO | disclosed |