SCHEMBL167919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3434578	0.89	ALDH1A1 (0.47)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL116437	0.86	ALDH1A1 (0.51)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL116629	0.84	LMNA (0.47)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL115542	0.83	LMNA (0.50)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL3434587	0.82	ALDH1A1 (0.58)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL3524088	0.81	LMNA (0.47)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL16104436	0.79	ALDH1A1 (0.42)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL13076010	0.79	ALDH1A1 (0.48)	LMNAALDH1A1MAPK1TP53GAA
	SCHEMBL3719295	0.77	MEN1 (0.49)	LMNAALDH1A1MAPK1TP53MEN1
	SCHEMBL115543	0.76	AKT1 (0.51)	LMNAAKT1MYLKMAPK14MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.