Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663924 | 0.81 | CA4 (0.35) | — | |
| SCHEMBL11516078 | 0.81 | OGG1 (0.38) | OGG1SLC6A4KCNH2HTR2ACNR1 | |
| SCHEMBL11661985 | 0.80 | L3MBTL1 (0.37) | SLC6A4HTR2APOLBAOC3MAOB | |
| SCHEMBL11660378 | 0.75 | CNR1 (0.38) | OGG1SLC6A4KCNH2HTR2ACNR1 | |
| SCHEMBL11665135 | 0.73 | PNMT (0.41) | MAOB | |
| SCHEMBL11614514 | 0.72 | OGG1 (0.38) | OGG1SLC6A4KCNH2HTR2ACNR1 | |
| SCHEMBL2318592 | 0.71 | WDR5 (0.42) | OGG1SLC6A4KCNH2HTR2APOLB | |
| SCHEMBL11518530 | 0.71 | POLB (0.37) | SLC6A4KCNH2HTR2ACNR1CNR2 | |
| SCHEMBL11664095 | 0.70 | PGR (0.37) | RELAOGG1KCNH2CNR1CNR2 | |
| SCHEMBL11660239 | 0.70 | WDR5 (0.46) | KCNH2CASRAOC3KMT2AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |