Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084229 | 0.80 | SLC6A2 (0.50) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL17045232 | 0.80 | PNMT (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL17045219 | 0.80 | PNMT (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL6683031 | 0.77 | SLC6A2 (0.52) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL5654864 | 0.77 | PNMT (0.60) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL14002931 | 0.77 | IDO1 (0.48) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL11666236 | 0.76 | IDO1 (0.46) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL5275709 | 0.75 | PPARG (0.54) | IDO1PNMTPPARGPPARANPC1 | |
| SCHEMBL7951780 | 0.75 | IDO1 (0.42) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL3669308 | 0.74 | PNMT (0.56) | IDO1PNMTTAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2010-06-10 | — | — | US | disclosed |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | IDO1 1114/4885PNMT 3501/4885TAAR1 2859/4885 |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | IDO1 1114/4885PNMT 3501/4885TAAR1 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.