Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668288 | 0.82 | MAOA (0.44) | SIGMAR1ALDH1A1MAPK1MAOAKMT2A | |
| SCHEMBL26008396 | 0.81 | HTR2C (0.42) | SIGMAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL25356724 | 0.80 | CCR2 (0.43) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL30623400 | 0.80 | CCR2 (0.43) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL26008714 | 0.76 | KDM1A (0.40) | SIGMAR1HTR2AALDH1A1MAPTPARP1 | |
| SCHEMBL7289989 | 0.75 | MAOA (0.38) | HTR2AHTR2CHTR2BMAOATSHR | |
| SCHEMBL4977596 | 0.73 | KDM1A (0.40) | SIGMAR1HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL25359962 | 0.73 | HTR2C (0.46) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL11674005 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTTSHRLMNAKMT2A | |
| SCHEMBL4975911 | 0.72 | DPP4 (0.40) | SIGMAR1HTR2AHTR2CHTR2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036842-A | FRIEDEL CRAFTS CATALYST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-4021451-A | P-(3,4-DIHYDRO-1-METHYL-1H-(1)BENZOTHIENO(2,3-C)PYRAN-1-YL)PHENYL) -ACETIC ACID | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |