Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14570581 | 0.91 | ACHE (0.46) | ACHEOPRM1OPRD1OPRK1LTA4H | |
| SCHEMBL9441932 | 0.80 | PTPN1 (0.46) | PTPN1BACE1 | |
| SCHEMBL2967942 | 0.79 | OPRM1 (0.59) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14143096 | 0.78 | OPRM1 (0.60) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12290753 | 0.77 | ESR1 (0.50) | OPRM1OPRD1OPRK1 | |
| SCHEMBL18594867 | 0.76 | P4HB (0.49) | OPRM1OPRD1OPRK1LTA4H | |
| SCHEMBL386761 | 0.76 | P4HB (0.49) | OPRM1OPRD1OPRK1LTA4H | |
| SCHEMBL31545866 | 0.76 | ACHE (0.41) | ACHELTA4HBACE1 | |
| SCHEMBL11677284 | 0.74 | GPR84 (0.50) | OPRM1OPRD1OPRK1LTA4H | |
| SCHEMBL11859205 | 0.72 | GPR84 (0.56) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007207-A | HYPOTENSIVE, ANTIDEPRESSANT, ANALGESIC, ANTICONVULSANT, SEDATIVE, TRANQUILIZER | SHARPS ASSOCIATES (US) | 1977-02-08 | — | — | US | disclosed |
| US-3992550-A | ANALGESICS, TRANQUILIZERS, ANTICONVULSANTS, ANTIHYPERTENSIVE AGENTS | SHARPS ASSOCIATES (US) | 1976-11-16 | — | — | US | disclosed |
| US-3946111-A | ANALYGESICS | SHARPS ASSOCIATES (US) | 1976-03-23 | — | — | US | disclosed |