Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798128 | 0.85 | TRPV1 (0.37) | TMEM97SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL11677856 | 0.81 | HTT (0.39) | SIGMAR1KCNH2HTTKMT2ANPC1 | |
| SCHEMBL11554624 | 0.77 | CYP1A2 (0.43) | TMEM97SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL11677519 | 0.76 | MMP2 (0.38) | TMEM97SIGMAR1KCNH2HTTMMP2 | |
| SCHEMBL11675971 | 0.74 | HRH3 (0.41) | SIGMAR1HTTTP53TSHRKDM4E | |
| SCHEMBL11782472 | 0.74 | HRH1 (0.58) | SIGMAR1KCNH2KDM4EHRH1 | |
| SCHEMBL30293069 | 0.73 | GRIN2D (0.40) | MMP2MMP3MEN1KMT2ANPC1 | |
| SCHEMBL11679975 | 0.73 | KDM4E (0.52) | HTTMEN1KMT2ANPC1TP53 | |
| SCHEMBL11680152 | 0.72 | SIGMAR1 (0.58) | SIGMAR1KDM4EHRH1 | |
| Hydrochloric Acid SCHEMBL11678798 | 0.71 | SIGMAR1 (0.56) | TMEM97SIGMAR1KDM4EHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |