Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678845 | 0.82 | NPC1 (0.57) | SIGMAR1POLBLSSTHRATHRB | |
| SCHEMBL11784879 | 0.81 | SIGMAR1 (0.60) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11780956 | 0.80 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL11562471 | 0.77 | SIGMAR1 (0.60) | SIGMAR1HTTKCNH2 | |
| SCHEMBL11681318 | 0.76 | SIGMAR1 (0.68) | SIGMAR1KCNH2 | |
| SCHEMBL11677632 | 0.75 | ALDH1A1 (0.60) | THRATHRBKMT2AHTT | |
| SCHEMBL19043651 | 0.74 | ALDH1A1 (0.56) | SIGMAR1POLBLSSKMT2AHTT | |
| SCHEMBL4984757 | 0.73 | SIGMAR1 (0.63) | SIGMAR1POLBTHRATHRBKMT2A | |
| SCHEMBL11680844 | 0.73 | ALDH1A1 (0.65) | THRATHRBKMT2AHTT | |
| SCHEMBL8948040 | 0.73 | HTR1A (0.61) | SIGMAR1POLBLSSHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |