Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11773142 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL9505592 | 0.80 | TAS2R38 (0.48) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL10401175 | 0.80 | SMN1; SMN2 (0.80) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11674215 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11238734 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11689139 | 0.78 | EPHX1 (0.58) | SMN1; SMN2TP53EPHX1TSHRNPC1 | |
| SCHEMBL10734509 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL23069093 | 0.76 | RAB9A (0.77) | SMN1; SMN2TP53TSHRNPC1RAB9A | |
| SCHEMBL2887905 | 0.76 | NPC1 (0.70) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL8428905 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017529-A | Herbicidal allophanimidates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |