Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298468 | 1.00 | KDM4E (0.61) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| Hydrochloric Acid SCHEMBL28150491 | 0.98 | ALDH1A1 (0.63) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| Hydrochloric Acid SCHEMBL3748898 | 0.98 | ALDH1A1 (0.63) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL7039823 | 0.86 | KDM4E (0.67) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL7623660 | 0.81 | ADRB2 (0.52) | LMNAHIF1AADRB2TDP1TSHR | |
| SCHEMBL1430589 | 0.81 | ADRB2 (0.52) | LMNAHIF1AADRB2TDP1TSHR | |
| SCHEMBL3688149 | 0.80 | TSHR (0.50) | LMNAHIF1AADRB2TDP1ALOX15 | |
| SCHEMBL24645195 | 0.79 | ADRB2 (0.50) | LMNAHIF1AADRB2TDP1TSHR | |
| SCHEMBL18660840 | 0.79 | KDM4E (0.64) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL6446911 | 0.79 | KDM4E (0.64) | KDM4ELMNAHIF1AADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175006-B2 | Compositions and methods for cyclofructans as separation agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2443127-A2 | COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS | Board of Regents, The University of Texas System (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20110024292-A1 | COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2011-02-03 | — | — | US | disclosed |
| WO-2010148191-A2 | COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20060252780-A1 | Fused pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1637532-A1 | FUSED PYRIMIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110024292-A1 | COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS | PAICS, DCXR, PFAS | KDM4E 4235/4885LMNA 3162/4885HIF1A 3245/4885 |
| US-20060252780-A1 | Fused pyrimidine derivatives | INSR, GPR119, NPY4R | KDM4E 1514/4885LMNA 4671/4885HIF1A 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.