Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.30 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683452 | 0.88 | TP53 (0.41) | TSHRGRIN2BKMT2ARXFP1TP53 | |
| Aniline SCHEMBL11683612 | 0.84 | PRMT1 (0.38) | TSHRALDH1A1CYP3A4HSD17B10KMT2A | |
| 3-Chloroaniline SCHEMBL11684018 | 0.84 | ALDH1A1 (0.44) | TSHRALDH1A1HSD17B10KMT2ARXFP1 | |
| SCHEMBL11682698 | 0.82 | LMNA (0.33) | — | |
| SCHEMBL11684152 | 0.75 | TSHR (0.42) | TSHRTHRBALDH1A1CYP3A4HPGD | |
| Aniline SCHEMBL11685961 | 0.70 | PRSS1 (0.37) | TSHRALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL11684369 | 0.70 | TSHR (0.44) | TSHRTHRBALDH1A1CYP3A4HPGD | |
| SCHEMBL11684625 | 0.70 | SENP3 (0.43) | TSHRALDH1A1HSD17B10KMT2ATP53 | |
| SCHEMBL11716204 | 0.70 | CYP3A4 (0.57) | TSHRTHRBALDH1A1CYP3A4HPGD | |
| SCHEMBL29581044 | 0.69 | PNMT (0.54) | CYP3A4IDO1KMT2ARXFP1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |