Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186920 | 0.83 | TDP1 (0.46) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL6705063 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL8579781 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL96214 | 0.71 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL131082 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL181965 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL1547930 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL5781095 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL4871529 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1TDP1CYP1A2 | |
| Bromide SCHEMBL11298934 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027039-A | ADMINISTERING AMINOGUANIDINE, GUANIDINE, OR 1-(SEC-BUTYLIDENEAMINO)GUANIDINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |