Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | MC3R | P41968 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
| ▸ | GABRE | P78334 | 1/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757670 | 0.87 | GABRA1 (0.53) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL4564319 | 0.87 | GABRP (0.68) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL29575850 | 0.87 | GABRP (0.68) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL11683712 | 0.86 | GABRA1 (0.52) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL11460474 | 0.84 | LMNA (0.65) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL11479334 | 0.81 | NISCH (0.53) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7308583 | 0.80 | GABRA1 (0.76) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7376244 | 0.79 | CHRM1 (0.73) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL11035945 | 0.79 | NISCH (0.60) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL31150913 | 0.79 | CHRM1 (0.62) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044003-A | Process for preparing 1,4-benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-08-23 | — | — | US | disclosed |