Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722741 | 0.80 | MAPT (0.43) | ELANELMNATP53TYMSKDM4E | |
| SCHEMBL11420639 | 0.67 | ACHE (0.39) | LMNATP53KDM4ETDP1NQO2 | |
| SCHEMBL5040647 | 0.64 | LMNA (0.39) | ELANELMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL15257485 | 0.63 | LMNA (0.41) | ELANELMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL10943121 | 0.61 | SLC2A1 (0.45) | TP53KDM4EL3MBTL1DHFRALDH1A1 | |
| SCHEMBL9722749 | 0.61 | G6PD (0.41) | LMNAKDM4EDHFRALDH1A1HSD17B10 | |
| SCHEMBL9722807 | 0.61 | HTT (0.44) | TYMS | |
| SCHEMBL14185473 | 0.61 | LMNA (0.39) | ELANELMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL9722805 | 0.61 | NR4A2 (0.47) | LMNATYMSKDM4EMAPK1ALDH1A1 | |
| SCHEMBL9722771 | 0.61 | BACE1 (0.40) | TYMSKDM4EL3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |