Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687340 | 0.81 | ALDH1A1 (0.50) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11324456 | 0.75 | L3MBTL1 (0.46) | TSHRALDH1A1CYP1A2TP53 | |
| SCHEMBL11685789 | 0.74 | MCOLN3 (0.59) | LMNATSHRALDH1A1MCOLN3KMT2A | |
| SCHEMBL11688729 | 0.74 | ALDH1A1 (0.53) | LMNATSHRALDH1A1MCOLN3SMN1; SMN2 | |
| SCHEMBL8990126 | 0.74 | CA1 (0.39) | TSHRALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL14100452 | 0.74 | ALDH1A1 (0.46) | LMNATSHRALDH1A1MCOLN3KMT2A | |
| SCHEMBL9247953 | 0.72 | KMT2A (0.47) | LMNATSHRALDH1A1MCOLN3KMT2A | |
| SCHEMBL11688661 | 0.72 | MCOLN3 (0.47) | LMNATSHRALDH1A1MCOLN3KMT2A | |
| SCHEMBL198040 | 0.71 | SMN1; SMN2 (0.65) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11689995 | 0.71 | ALDH1A1 (0.54) | LMNATSHRALDH1A1MCOLN3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |