Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KCNJ6 | P48051 | 5/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688036 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TSHRGLAMAPTAPEX1 | |
| SCHEMBL11685240 | 0.81 | LMNA (0.49) | ALDH1A1TSHRLMNASMN1; SMN2MEN1 | |
| SCHEMBL11324456 | 0.79 | L3MBTL1 (0.46) | ALDH1A1TSHRCYP3A4POLBCYP1A1 | |
| SCHEMBL8990126 | 0.78 | CA1 (0.39) | ALDH1A1TSHRMAPTCYP3A4ALOX15 | |
| SCHEMBL7217939 | 0.74 | KCNJ6 (0.61) | ALDH1A1TSHRGLAKCNJ6KCNJ5 | |
| SCHEMBL2061935 | 0.73 | ALDH1A1 (0.61) | ALDH1A1TSHRGLAKCNJ6KCNJ5 | |
| SCHEMBL11684852 | 0.71 | ALDH1A1 (0.69) | ALDH1A1TSHRGLAKCNJ6KCNJ5 | |
| SCHEMBL203946 | 0.71 | CYP3A4 (0.58) | ALDH1A1TSHRMAPTCYP3A4LMNA | |
| SCHEMBL29451695 | 0.69 | ALDH1A1 (0.52) | ALDH1A1TSHRGLAKCNJ6KCNJ5 | |
| SCHEMBL7213914 | 0.69 | TSHR (0.59) | ALDH1A1TSHRGLAKCNJ6KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |