Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12087097 | 0.78 | VCAM1 (0.51) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL10882114 | 0.76 | F2 (0.40) | ALDH1A1TSHRKDM4E | |
| SCHEMBL12576014 | 0.76 | HTT (0.47) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL11685240 | 0.74 | LMNA (0.49) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL8540726 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL11689995 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL17000446 | 0.71 | GAA (0.43) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL10691315 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTTSHRKDM4E | |
| SCHEMBL9247953 | 0.69 | KMT2A (0.47) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL198040 | 0.68 | SMN1; SMN2 (0.65) | ALDH1A1KMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |