Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685618 | 0.85 | ALDH1A1 (0.43) | ALDH1A1RECQLTDP1HSD17B10LMNA | |
| SCHEMBL11686703 | 0.83 | ACLY (0.46) | ALDH1A1ESR1NSD2POLBAPEX1 | |
| SCHEMBL753487 | 0.73 | NSD2 (0.41) | ALDH1A1ESR1NSD2POLBAPEX1 | |
| SCHEMBL11657083 | 0.72 | ALDH1A1 (0.47) | ALDH1A1POLBRECQLHSD17B10LMNA | |
| SCHEMBL11683195 | 0.71 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNAMAPTKMT2A | |
| Methane SCHEMBL11681369 | 0.71 | ALDH1A1 (0.46) | ALDH1A1POLBRECQLHSD17B10LMNA | |
| SCHEMBL11283353 | 0.71 | ALDH1A1 (0.47) | ALDH1A1RECQLHSD17B10LMNARAB9A | |
| SCHEMBL11683080 | 0.70 | LMNA (0.41) | ALDH1A1ESR1NSD2POLBAPEX1 | |
| SCHEMBL10691315 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HSD17B10LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL6850443 | 0.70 | ALDH1A1 (0.38) | ALDH1A1ESR1TDP1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |