Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685561 | 0.85 | PSEN1 (0.38) | ALDH1A1LMNASMN1; SMN2CYP2C9HSD17B10 | |
| SCHEMBL11657083 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAMCOLN3HSD17B10CA2 | |
| SCHEMBL11682666 | 0.81 | KDM4E (0.45) | ALDH1A1LMNAMCOLN3HSD17B10TSHR | |
| Methane SCHEMBL11681369 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAMCOLN3HSD17B10CA2 | |
| Methane SCHEMBL11682364 | 0.81 | KDM4E (0.44) | ALDH1A1LMNAMCOLN3HSD17B10TSHR | |
| SCHEMBL11683195 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNAGAANPSR1KMT2A | |
| SCHEMBL11684844 | 0.72 | L3MBTL1 (0.46) | ALDH1A1LMNAGAATSHRKMT2A | |
| SCHEMBL11686703 | 0.72 | ACLY (0.46) | ALDH1A1LMNASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL11680630 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2MCOLN3HSD17B10 | |
| SCHEMBL11681382 | 0.71 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2MCOLN3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |