Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670628 | 0.78 | LMNA (0.47) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10145040 | 0.78 | ALDH1A1 (0.69) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1828426 | 0.77 | ALDH1A1 (0.54) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1156438 | 0.77 | LMNA (0.50) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3160516 | 0.77 | ALDH1A1 (0.52) | LMNAMAPK1ALDH1A1HSD11B1MEN1 | |
| SCHEMBL517720 | 0.75 | ALDH1A1 (0.52) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7937243 | 0.75 | ALDH1A1 (0.52) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11521879 | 0.75 | ALDH1A1 (0.50) | MAPK1HTTSMN1; SMN2ALDH1A1KIF11 | |
| SCHEMBL14194270 | 0.74 | KIF11 (0.52) | ALDH1A1KIF11HSD11B1CNR2 | |
| SCHEMBL6849852 | 0.73 | CA2 (0.57) | LMNAMAPK1HTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |