Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281214 | 0.76 | LMNA (0.52) | MAOAMAOBLMNASMN1; SMN2MAPT | |
| SCHEMBL1538590 | 0.76 | PTPN1 (0.48) | TSHRALDH1A1PTPN1 | |
| SCHEMBL7534910 | 0.74 | TSHR (0.46) | TSHRALDH1A1PTPN1 | |
| SCHEMBL7708311 | 0.74 | MAOA (0.48) | MAOAMAOBLMNASMN1; SMN2MAPT | |
| SCHEMBL6512980 | 0.71 | PDE7A (0.41) | TSHRSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL11757526 | 0.71 | TSHR (0.55) | TSHRPTPN1 | |
| SCHEMBL6522327 | 0.70 | TSHR (0.39) | TSHRSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL5069170 | 0.70 | TSHR (0.46) | TSHRMAOAMAOBSMN1; SMN2MAPT | |
| Isobutane SCHEMBL27649309 | 0.69 | UGT2B7 (0.44) | TSHRLMNAHTR2CPTPN1MEN1 | |
| SCHEMBL6513987 | 0.69 | TSHR (0.38) | TSHRSMN1; SMN2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |