Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670749 | 0.84 | TSHR (0.61) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 | |
| SCHEMBL11859442 | 0.82 | KIF11 (0.44) | TSHRCYP1A2ALDH1A1CYP3A4SLC6A4 | |
| SCHEMBL151981 | 0.82 | TSHR (0.65) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 | |
| SCHEMBL28193891 | 0.79 | TSHR (0.61) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL31241190 | 0.79 | TSHR (0.61) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 | |
| Hydrochloric Acid SCHEMBL15864874 | 0.79 | TSHR (0.61) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 | |
| SCHEMBL16046942 | 0.76 | ESR1 (0.58) | TSHRMAOAMAOBALDH1A1HPGD | |
| SCHEMBL7646185 | 0.75 | TSHR (0.50) | TSHRCYP1A2MAPK1 | |
| SCHEMBL7649802 | 0.75 | KIF11 (0.54) | TSHRCYP1A2ALDH1A1KCNN4CYP3A4 | |
| SCHEMBL7644095 | 0.73 | TSHR (0.48) | TSHRCYP1A2ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361776-B2 | Zero-valent transition metal complex and method for producing an organometallic compound using the same as a starting material | SEKISUI CHEMICAL CO., LTD. (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20060149088-A1 | Zero-valence transition metal complex and method of synthesizing organometallic compound from the same as starting material | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149088-A1 | Zero-valence transition metal complex and method of synthesizing organometallic compound from the same as starting material | OSTC, PORCN, SQLE | TSHR 4126/4885MAOA 585/4885MAOB 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.