Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | EDNRB | P24530 | 3/20 | 0.53 |
| ▸ | EDNRA | P25101 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395399 | 0.80 | ATM (0.47) | EDNRBEDNRAMAPTALDH1A1KDM4E | |
| SCHEMBL6881129 | 0.77 | ACHE (0.63) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL1520733 | 0.75 | SIRT1 (0.45) | MTNR1AMTNR1BACHE | |
| SCHEMBL10623445 | 0.72 | ALDH1A1 (0.64) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5337855 | 0.72 | MAPK14 (0.67) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21465813 | 0.72 | ATM (0.45) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL5158375 | 0.72 | LMNA (0.55) | ALDH1A1SMN1; SMN2KDM4EGAALMNA | |
| SCHEMBL11199810 | 0.71 | — | — | |
| SCHEMBL3759572 | 0.70 | MAPK14 (0.64) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10692678 | 0.70 | METAP1 (0.63) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041173-A | ANTI-ASTHMATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-09 | — | — | US | disclosed |