Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502222 | 0.87 | HCAR3 (1.00) | HCAR3ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL11697178 | 0.83 | HCAR3 (0.74) | HCAR3ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL9503759 | 0.78 | PDK1 (0.70) | HCAR3ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL16157208 | 0.78 | MEN1 (1.00) | HCAR3ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL1524806 | 0.76 | ALDH3A1 (0.65) | HCAR3ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL11749054 | 0.76 | PDK1 (0.58) | HCAR3ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1966463 | 0.76 | CASP6 (0.69) | HCAR3ALDH1A1PDK1TSHRVCAM1 | |
| SCHEMBL29492133 | 0.76 | CASP6 (0.69) | HCAR3ALDH1A1PDK1TSHRVCAM1 | |
| SCHEMBL11800468 | 0.75 | HCAR3 (0.80) | HCAR3ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL1609387 | 0.75 | PDK1 (0.54) | HCAR3ALDH1A1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052444-A | DIAZO COUPLERS FOR MONOAZO DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |