Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29680677 | 0.77 | MAOA (0.57) | KMT2AMAOBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL86392 | 0.73 | MAPT (0.67) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL29375440 | 0.73 | MAPT (0.67) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL1542289 | 0.73 | KMT2A (0.50) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL11696253 | 0.72 | PKM (0.55) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL28709151 | 0.71 | PKM (0.63) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL11660603 | 0.71 | MAOB (0.55) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL6966321 | 0.70 | PKM (1.00) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL2197988 | 0.69 | MAPK14 (0.58) | PKMTSHRKMT2AMAOBMAPT | |
| SCHEMBL3553528 | 0.68 | PKM (0.59) | PKMTSHRKMT2AMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012411-A | Heterocyclic annelated 1-benzoxepin-5-ones | WARNER-LAMBERT COMPANY (US) | 1977-03-15 | — | — | US | disclosed |