Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263489 | 0.87 | NR1I2 (0.42) | ESR1ESR2CYP3A4LMNACYP1A2 | |
| SCHEMBL14330440 | 0.82 | CYP19A1 (0.45) | CYP19A1ESR1ESR2CYP3A4LMNA | |
| SCHEMBL11696345 | 0.79 | LMNA (0.47) | CYP19A1ESR1ESR2CYP3A4LMNA | |
| SCHEMBL8410387 | 0.78 | SLC6A4 (0.36) | ESR1ESR2CYP3A4LMNACYP1A2 | |
| SCHEMBL5704306 | 0.78 | ALDH1A1 (0.44) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5749794 | 0.78 | ESR1 (0.58) | CYP19A1ESR1ESR2CYP3A4LMNA | |
| SCHEMBL19453319 | 0.77 | LOXL2 (0.48) | — | |
| SCHEMBL2015853 | 0.76 | MAOA (0.55) | CYP3A4LMNAMAOATSHRMEN1 | |
| SCHEMBL5178198 | 0.76 | MAOA (0.47) | CYP3A4CYP1A2MAOACYP2C9CYP2C19 | |
| SCHEMBL10413993 | 0.76 | MAOA (0.55) | LMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106468802-A | Light guide plate compositionss, light guide plate and its preparation method, side light emitting-type surface illuminating device | JSR株式会社 | 2017-03-01 | — | — | CN | disclosed |
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |
| US-4008275-A | Process for isolating 4,4'-diaminodiphenylmethane | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |