Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906995 | 0.84 | RECQL (0.56) | RECQLKMT2AMEN1L3MBTL1GALR3 | |
| SCHEMBL1169145 | 0.82 | GALR3 (0.56) | RECQLKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL1168814 | 0.81 | SMN1; SMN2 (0.52) | RECQLKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1169304 | 0.77 | P2RX7 (0.47) | KMT2ATDP1L3MBTL1SMN1; SMN2P2RX7 | |
| SCHEMBL12991853 | 0.76 | BDKRB1 (0.57) | KMT2APKMTDP1L3MBTL1HPGD | |
| SCHEMBL1168961 | 0.76 | HTT (0.47) | KMT2ATDP1L3MBTL1HPGDCNR2 | |
| SCHEMBL1169382 | 0.76 | ALDH1A1 (0.54) | KMT2APKMTDP1L3MBTL1HPGD | |
| SCHEMBL4520630 | 0.75 | LMNA (0.57) | KMT2APKMTDP1L3MBTL1HPGD | |
| SCHEMBL1169638 | 0.74 | CNR2 (0.43) | KMT2ATDP1L3MBTL1SMN1; SMN2P2RX7 | |
| SCHEMBL28000208 | 0.74 | GALR3 (0.60) | RECQLKMT2AMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959414-B | Herbicidal compounds | SYNGENTA LTD | 2015-03-25 | — | — | CN | disclosed |
| US-8987455-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2015-03-24 | — | — | US | disclosed |
| US-8987455-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2015-03-24 | — | — | US | disclosed |
| US-8987455-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2015-03-24 | — | — | US | disclosed |
| US-8557840-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-10-15 | — | — | US | disclosed |
| US-8557840-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-10-15 | — | — | US | disclosed |
| US-8557840-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-10-15 | — | — | US | disclosed |
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-10 | — | — | US | disclosed |
| EP-2254417-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009090401-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
| WO-2009090401-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034334-A1 | HERBICIDAL COMPOUNDS | CYP4Z1, CYP4F3, DDT | RECQL 539/4885KMT2A 1635/4885MEN1 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.