Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24009068 | 0.75 | EGFR (0.41) | EGFRERBB2ALDH1A1 | |
| SCHEMBL24009071 | 0.75 | SLC6A3 (0.40) | EGFRERBB2HTTPLAU | |
| SCHEMBL17128052 | 0.75 | KDM4E (0.39) | EGFRERBB2HTTKDM4EMEN1 | |
| SCHEMBL31716247 | 0.75 | KDM4E (0.39) | EGFRERBB2HTTKDM4EMEN1 | |
| SCHEMBL1344423 | 0.73 | LRRK2 (0.54) | EGFRERBB2HTTKDM4EMEN1 | |
| SCHEMBL28655839 | 0.71 | ALDH1A1 (0.47) | DYRK1AHTTKDM4EMEN1KMT2A | |
| SCHEMBL30950239 | 0.71 | ALDH1A1 (0.47) | DYRK1AHTTKDM4EMEN1KMT2A | |
| SCHEMBL28311760 | 0.71 | PABPC1 (0.36) | HTTKDM4EMEN1KMT2AUSP2 | |
| SCHEMBL22118253 | 0.70 | ALDH1A1 (0.48) | HTTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL28311761 | 0.70 | KDM4E (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035368-A | ANTI-ALLERGIC | RIKER LABORATORIES, INC. (US) | 1977-07-12 | — | — | US | disclosed |