Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703552 | 0.91 | THRB (0.41) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1355167 | 0.81 | ALDH1A1 (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL10073435 | 0.78 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19844235 | 0.78 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19789498 | 0.78 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3477916 | 0.78 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11703566 | 0.77 | TBXAS1 (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19906406 | 0.76 | TSHR (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11703864 | 0.75 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL14050216 | 0.74 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054232-A | CROSSLINKED 2-ACETOACETOXYETHYL METHACRYLATE HOMOPOLYMER OR COPOLYMER | EASTMAN KODAK COMPANY (US) | 1977-10-18 | — | — | US | disclosed |