Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710375 | 0.78 | CNR2 (0.57) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL11802836 | 0.78 | GAA (0.57) | HCAR3LMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11709751 | 0.78 | CNR2 (0.56) | KMT2AMEN1ALDH1A1HTTKDM4E | |
| SCHEMBL11847710 | 0.74 | HCAR3 (0.47) | KMT2AMEN1HCAR3LMNAALDH1A1 | |
| SCHEMBL30241160 | 0.72 | MAPT (0.44) | KMT2AMEN1HCAR3LMNAALDH1A1 | |
| SCHEMBL28945979 | 0.72 | MAPT (0.44) | KMT2AMEN1HCAR3LMNAALDH1A1 | |
| SCHEMBL135289 | 0.71 | CASP6 (0.47) | KMT2AMEN1HCAR3LMNAALDH1A1 | |
| SCHEMBL11712878 | 0.70 | KMT2A (0.58) | KMT2AMEN1LMNAPPARG | |
| SCHEMBL11849884 | 0.70 | HCAR3 (0.56) | KMT2AMEN1HCAR3LMNAGPR55 | |
| SCHEMBL7826598 | 0.70 | VCAM1 (0.49) | KMT2AMEN1HCAR3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010193-A | (ALKYLAMINO)ALKYL SUBSTITUTED BENZOATES, LOCAL ANESTHETIC, ANTIFIBRILLATORY, ANTIARRHYTHMIAL | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1977-03-01 | — | — | US | disclosed |