Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 9/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436643 | 0.83 | CA12 (0.52) | GAAMAPTCA12CA9ALDH1A1 | |
| SCHEMBL28945979 | 0.82 | MAPT (0.44) | GAAMAPTHCAR3ALDH1A1VCAM1 | |
| SCHEMBL30241160 | 0.82 | MAPT (0.44) | GAAMAPTHCAR3ALDH1A1VCAM1 | |
| SCHEMBL11847710 | 0.81 | HCAR3 (0.47) | GAAMAPTHCAR3CA12CA9 | |
| SCHEMBL11843602 | 0.80 | ALDH1A1 (0.55) | GAAMAPTHCAR3CA12CA9 | |
| SCHEMBL11704303 | 0.78 | KMT2A (0.45) | MAPTHCAR3ALDH1A1LMNA | |
| SCHEMBL7826598 | 0.77 | VCAM1 (0.49) | GAAMAPTHCAR3ALDH1A1CYP1A2 | |
| SCHEMBL28765728 | 0.76 | GAA (0.45) | GAAMAPTHCAR3VCAM1 | |
| SCHEMBL135289 | 0.76 | CASP6 (0.47) | GAAMAPTHCAR3ALDH1A1CYP1A2 | |
| SCHEMBL11595503 | 0.75 | POLB (0.56) | GAAMAPTCA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992440-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |
| US-3982018-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |