Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30241160 | 1.00 | MAPT (0.44) | MAPTMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL11847710 | 0.86 | HCAR3 (0.47) | MAPTMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL7826598 | 0.82 | VCAM1 (0.49) | MAPTMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL11802836 | 0.82 | GAA (0.57) | MAPTALDH1A1GAAHCAR3VCAM1 | |
| SCHEMBL135289 | 0.80 | CASP6 (0.47) | MAPTMEN1ALDH1A1KMT2AGAA | |
| Methylamine SCHEMBL11877019 | 0.80 | TSHR (0.44) | MAPTMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL31108456 | 0.79 | ALDH1A1 (0.57) | MEN1ALDH1A1KMT2AHCAR3KDM4E | |
| SCHEMBL573259 | 0.79 | ALDH1A1 (0.57) | MEN1ALDH1A1KMT2AHCAR3KDM4E | |
| SCHEMBL573520 | 0.78 | HCAR3 (0.47) | MAPTMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL28945995 | 0.77 | ALDH1A1 (0.44) | MAPTMEN1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677544-A | Preparation method of bumetanide | 中科苏州药物研究院 | 2023-02-03 | — | — | CN | disclosed |
| CN-115677544-A | Preparation method of bumetanide | 中科苏州药物研究院 | 2023-02-03 | — | — | CN | disclosed |