Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361052 | 0.95 | LTB4R2 (0.47) | LTB4R2KDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL4153728 | 0.86 | ACHE (0.52) | LTB4R2ACHEALDH1A1CHRM1CHRM3 | |
| SCHEMBL27498004 | 0.79 | CHRM1 (0.51) | LTB4R2KDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL8804207 | 0.79 | LCK (0.50) | LTB4R2KDM4EACHEALDH1A1 | |
| SCHEMBL11225170 | 0.79 | CHRM5 (0.60) | ACHEALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL10099720 | 0.77 | MEN1 (0.62) | LTB4R2ACHEALDH1A1 | |
| SCHEMBL27658528 | 0.74 | KDM4E (0.48) | LTB4R2KDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL7811362 | 0.74 | LTB4R (0.56) | LTB4R2KDM4EFFAR1ALDH1A1 | |
| SCHEMBL27572248 | 0.73 | CHRM5 (0.62) | KDM4EALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL6901088 | 0.73 | RCE1 (0.53) | KDM4EOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |