Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404339 | 0.84 | TAAR1 (0.44) | TDP1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL470870 | 0.81 | P2RX7 (0.43) | TDP1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL410563 | 0.81 | P2RX7 (0.43) | TDP1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27506411 | 0.81 | TAAR1 (0.44) | TDP1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4977025 | 0.79 | SLC18A3 (0.44) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL10409483 | 0.79 | SLC6A2 (0.40) | TDP1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL470840 | 0.78 | CHRNB2 (0.41) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL10958845 | 0.76 | SLC18A3 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL10409487 | 0.76 | SIGMAR1 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3TAAR1 | |
| Acetic Acid SCHEMBL27463978 | 0.75 | KCNH2 (0.43) | MAPTTAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012389-A | ANTICOAGULANTS | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1977-03-15 | — | — | US | disclosed |
| US-3935214-A | ANTICOAGULANT | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1976-01-27 | — | — | US | disclosed |