Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907406 | 0.81 | HSP90AA1 (0.54) | HSP90AA1MAPK1HIF1AALDH1A1PKM | |
| SCHEMBL65066 | 0.78 | HSP90AA1 (0.50) | HSP90AA1ALDH1A1MEN1KMT2ATSHR | |
| Bromide SCHEMBL6879691 | 0.77 | HSP90AA1 (0.49) | HSP90AA1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL2389657 | 0.77 | HCAR2 (0.57) | HSP90AA1MAPK1ALDH1A1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9061399 | 0.77 | HSP90AA1 (0.49) | HSP90AA1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL12305763 | 0.77 | HCAR2 (0.57) | HSP90AA1MAPK1ALDH1A1KMT2ATSHR | |
| SCHEMBL1501229 | 0.75 | PKM (0.54) | HSP90AA1MAPK1ALDH1A1PKMMEN1 | |
| SCHEMBL2392064 | 0.75 | LMNA (0.50) | HSP90AA1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6290042 | 0.75 | HSP90AA1 (0.47) | HSP90AA1MAPK1ALDH1A1PKMMEN1 | |
| SCHEMBL11686008 | 0.75 | LMNA (0.40) | MAPK1HIF1AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065620-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |