SCHEMBL7907406

SCHEMBL7907406

O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)OCCl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.54
USP2 O75604 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
ALDH1A1 P00352 4/20 0.35
HCAR2 Q8TDS4 2/20 0.35
POLB P06746 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPK1 P28482 2/20 0.34
TRPA1 O75762 1/20 0.34
GSK3B P49841 1/20 0.34
HIF1A Q16665 1/20 0.34
CFTR P13569 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA5A P35218 1/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65066 0.82 HSP90AA1 (0.50) HSP90AA1SMN1; SMN2ALDH1A1HCAR2POLB
SCHEMBL11707482 0.81 HSP90AA1 (0.46) HSP90AA1USP2SMN1; SMN2PKMALDH1A1
Bromide SCHEMBL6879691 0.81 HSP90AA1 (0.49) HSP90AA1SMN1; SMN2ALDH1A1HCAR2POLB
Hydrochloric Acid SCHEMBL9061399 0.81 HSP90AA1 (0.49) HSP90AA1SMN1; SMN2ALDH1A1POLBMEN1
SCHEMBL12305763 0.81 HCAR2 (0.57) HSP90AA1SMN1; SMN2ALDH1A1HCAR2POLB
SCHEMBL2389657 0.81 HCAR2 (0.57) HSP90AA1SMN1; SMN2ALDH1A1HCAR2POLB
SCHEMBL2392064 0.79 LMNA (0.50) HSP90AA1SMN1; SMN2ALDH1A1HCAR2POLB
SCHEMBL1501229 0.79 PKM (0.54) HSP90AA1SMN1; SMN2PKMALDH1A1MEN1
SCHEMBL6290042 0.79 HSP90AA1 (0.47) HSP90AA1USP2SMN1; SMN2PKMALDH1A1
SCHEMBL2597946 0.78 ALDH1A1 (0.49) HSP90AA1SMN1; SMN2ALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211397-B1 CHLORINATION OF PHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
EP-0603225-B1 PROCESS FOR PRODUCING alpha-CHLOR-METHYLEN-TRIORGANYLPHOSPHORANE DERIVATES BASF AG (DE) 1997-06-04 EP disclosed