Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305763 | 1.00 | HCAR2 (0.57) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11709722 | 0.87 | ATM (0.48) | HCAR2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10636434 | 0.85 | RAB9A (0.52) | ALDH1A1TDP1KMT2A | |
| SCHEMBL65066 | 0.81 | HSP90AA1 (0.50) | HCAR2LMNAALDH1A1HSP90AA1KMT2A | |
| SCHEMBL7907406 | 0.81 | HSP90AA1 (0.54) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| Bromide SCHEMBL6879691 | 0.79 | HSP90AA1 (0.49) | HCAR2LMNAALDH1A1HSP90AA1KMT2A | |
| Hydrochloric Acid SCHEMBL9061399 | 0.79 | HSP90AA1 (0.49) | LMNAALDH1A1HSP90AA1KMT2APOLB | |
| SCHEMBL2392064 | 0.78 | LMNA (0.50) | HCAR2LMNAALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6290042 | 0.78 | HSP90AA1 (0.47) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1501229 | 0.78 | PKM (0.54) | LMNAALDH1A1MAPK1HSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054877-A1 | Enantiomerically selective cyclopropanation | TAYLOR DENNIS (AU) | 2005-03-10 | — | — | US | claimed |
| US-20250312367-A1 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2025-10-09 | — | — | US | disclosed |
| EP-4619386-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-24 | — | — | EP | disclosed |
| EP-4577526-A1 | VHH ANTIBODY CONJUGATES | Abdera Therapeutics Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |
| EP-4522628-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-3788043-B1 | SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2024-09-17 | — | — | US | disclosed |
| WO-2024104932-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-23 | — | — | WO | disclosed |
| US-11964988-B2 | Fused heterocyclic compounds as RET kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2024-04-23 | — | — | US | disclosed |
| EP-0067518-B1 | MODIFIED BETA-LACTAM COMPOUNDS | BEECHAM GROUP PLC (GB) | 1985-08-21 | — | — | EP | disclosed |
| EP-0136721-A2 | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |
| EP-0035689-B1 | 4-SUBSTITUTED-2-OXOAZETIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE FOR PREPARING ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |
| US-4463010-A | 1-Aza-[3.2.0]-bicycloheptane-2-carboxylic acid, ester or salt thereof | BEECHAM GROUP P.L.C. (GB) | 1984-07-31 | — | — | US | disclosed |
| US-4383945-A | 4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-17 | — | — | US | disclosed |
| EP-0067518-A1 | Modified beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4361514-A | Carbon analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1982-11-30 | — | — | US | disclosed |
| EP-0035689-A1 | 4-Substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-16 | — | — | EP | disclosed |
| US-4282149-A | Carbon and oxygen analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4143046-A | CARBON AND OXYGEN ANALOGS OF PENICILLIN | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1979-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964988-B2 | Fused heterocyclic compounds as RET kinase inhibitors | RET, ROR1, FRK | HCAR2 1847/4885LMNA 2219/4885ALDH1A1 3607/4885 |
| US-20250312367-A1 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | POLRMT, TARDBP, NSUN2 | HCAR2 1701/4885LMNA 1138/4885ALDH1A1 3858/4885 |
| US-20050054877-A1 | Enantiomerically selective cyclopropanation | CDY1; CDY1B, DYRK2, DYRK4 | HCAR2 2026/4885LMNA 2016/4885ALDH1A1 1988/4885 |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | MCL1, BCL9, BCL2L1 | HCAR2 4790/4885LMNA 1191/4885ALDH1A1 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.