Sugi Predict

Sugi Predict / Compounds / SCHEMBL2392064

SCHEMBL2392064

SCHEMBL2392064

CCCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.50
▸ HSP90AA1 P07900 1/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ HCAR2 Q8TDS4 2/20 0.44
▸ GAA P10253 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ POLB P06746 1/20 0.41
▸ APP P05067 1/20 0.40
▸ HPGD P15428 2/20 0.40
▸ THRB P10828 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ TSHR P16473 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ CHRM1 P11229 1/20 0.38
▸ SLC6A2 P23975 1/20 0.38
▸ KDR P35968 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852873 0.90 TSHR (0.50) LMNAHSP90AA1ALDH1A1MEN1KMT2A
SCHEMBL65066 0.86 HSP90AA1 (0.50) LMNAHSP90AA1ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL9061399 0.85 HSP90AA1 (0.49) LMNAHSP90AA1ALDH1A1MEN1KMT2A
Bromide SCHEMBL6879691 0.85 HSP90AA1 (0.49) LMNAHSP90AA1ALDH1A1MEN1KMT2A
SCHEMBL6290042 0.83 HSP90AA1 (0.47) LMNAHSP90AA1ALDH1A1MEN1KMT2A
SCHEMBL22124863 0.83 HSP90AA1 (0.44) HSP90AA1ALDH1A1MEN1KMT2AHCAR2
SCHEMBL10467637 0.81 TSHR (0.45) LMNAHSP90AA1ALDH1A1MEN1KMT2A
SCHEMBL7907406 0.79 HSP90AA1 (0.54) LMNAHSP90AA1ALDH1A1MEN1KMT2A
SCHEMBL2597946 0.79 ALDH1A1 (0.49) LMNAHSP90AA1ALDH1A1SMN1; SMN2POLB
SCHEMBL12305763 0.78 HCAR2 (0.57) LMNAHSP90AA1ALDH1A1KMT2AHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246867-B Method for synthesizing 7-ketolithocholic acid by taking BA as raw material 江苏佳尔科药业集团股份有限公司 2026-05-12 — — CN claimed
CN-115536719-B Synthesis method of high-purity plant source 7-ketolithocholic acid 江苏佳尔科药业集团股份有限公司 2024-02-09 — — CN claimed
WO-2023207268-A1 SYNTHESIS METHOD OF PLANT-DERIVED DEOXYCHOLIC ACID 上海科骊科生物技术有限公司 2023-11-02 — — WO claimed
CN-116947953-A Synthesis method of plant source deoxycholic acid 上海科骊科生物技术有限公司 2023-10-27 — — CN claimed
CN-115536719-A Synthetic method of high-purity plant source 7-ketolithocholic acid 江苏佳尔科药业集团股份有限公司 2022-12-30 — — CN claimed
CN-115246867-A Method for synthesizing 7-ketolithocholic acid by taking BA as raw material 江苏佳尔科药业集团股份有限公司 2022-10-28 — — CN claimed
WO-2021109791-A1 METHOD FOR SYNTHESIZING URSODEOXYCHOLIC ACID USING BA AS RAW MATERIAL 江苏佳尔科药业集团股份有限公司 2021-06-10 — — WO claimed
CN-115246867-B Method for synthesizing 7-ketolithocholic acid by taking BA as raw material 江苏佳尔科药业集团股份有限公司 2026-05-12 — — CN disclosed
US-20240228488-A1 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN TAKEDA PHARMACEUTICALS CO (JP) 2024-07-11 — — US disclosed
CN-115536719-B Synthesis method of high-purity plant source 7-ketolithocholic acid 江苏佳尔科药业集团股份有限公司 2024-02-09 — — CN disclosed
WO-2023207268-A1 SYNTHESIS METHOD OF PLANT-DERIVED DEOXYCHOLIC ACID 上海科骊科生物技术有限公司 2023-11-02 — — WO disclosed
CN-116947953-A Synthesis method of plant source deoxycholic acid 上海科骊科生物技术有限公司 2023-10-27 — — CN disclosed
US-11723908-B2 Quinazoline derivatives as antitumor agents SUZHOU ZANRONG PHARMA LIMITED (CN) 2023-08-15 — — US disclosed
US-20180127378-A1 TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2018-05-10 — — US disclosed
US-9796683-B2 Tetrasubstituted alkene compounds and their use EISAI R&D MANAGEMENT CO., LTD. (JP) 2017-10-24 — — US disclosed
US-8471063-B2 Michael systems as transglutaminase inhibitors ZEDIRA GMBH (DE) 2013-06-25 — — US disclosed
US-20110229568-A1 MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS ZEDIRA GMBH (DE) 2011-09-22 — — US disclosed
US-4808749-A Cyclopropane carboxylic esters and acids ROUSSEL UCLAF (FR) 1989-02-28 — — US disclosed
US-4489093-A Insecticidal esters ROUSSEL UCLAF (FR) 1984-12-18 — — US disclosed
US-4065620-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1977-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228488-A1 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK5, KLK1 LMNA 1541/4885HSP90AA1 3197/4885ALDH1A1 3026/4885
US-11723908-B2 Quinazoline derivatives as antitumor agents ABL1, TP53, JAK1 LMNA 3486/4885HSP90AA1 1191/4885ALDH1A1 3405/4885
US-20110229568-A1 MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS TGM2, TGM3, TGM1 LMNA 1967/4885HSP90AA1 847/4885ALDH1A1 4170/4885
US-20180127378-A1 TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE BRCA1, ESR2, ESR1 LMNA 3864/4885HSP90AA1 736/4885ALDH1A1 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.