Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.55 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704133 | 0.87 | NPC1 (0.74) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL11731227 | 0.76 | NPC1 (0.55) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL22235922 | 0.76 | RAB9A (0.57) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL10061821 | 0.75 | GAA (0.67) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5361880 | 0.73 | HDAC1 (0.74) | SMN1; SMN2KMT2ACYP3A4LMNAHDAC1 | |
| SCHEMBL22236216 | 0.73 | HDAC1 (0.53) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL31006498 | 0.73 | PTGS2 (0.68) | CYP3A4LMNAHDAC1HDAC6GAA | |
| SCHEMBL11832072 | 0.73 | PTGS2 (0.68) | CYP3A4LMNAHDAC1HDAC6GAA | |
| SCHEMBL27435813 | 0.72 | LMNA (0.59) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL5361922 | 0.72 | GAA (0.77) | KMT2AHTTCYP3A4LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |