Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.33 |
| ▸ | NAAA | Q02083 | 4/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PRKCB | P05771 | 2/20 | 0.31 |
| ▸ | PRKCH | P24723 | 2/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TK1 | P04183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947911 | 1.00 | RAB9A (0.33) | RAB9AKDM4ENPC1SMN1; SMN2PRKCA | |
| SCHEMBL8947577 | 0.83 | — | — | |
| SCHEMBL8948021 | 0.80 | PRKCA (0.38) | RAB9AKDM4ENPC1SMN1; SMN2PRKCA | |
| SCHEMBL8947915 | 0.80 | PRKCA (0.38) | RAB9AKDM4ENPC1SMN1; SMN2PRKCA | |
| SCHEMBL4533210 | 0.77 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1366222 | 0.77 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1365456 | 0.73 | TK1 (0.30) | TK1 | |
| SCHEMBL11709167 | 0.71 | GRM2 (0.32) | — | |
| SCHEMBL1364377 | 0.70 | RAB9A (0.38) | RAB9AKDM4ENPC1SMN1; SMN2PRKCA | |
| SCHEMBL16976906 | 0.65 | RAB9A (0.39) | RAB9AKDM4ENPC1SMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486540-A | Cyclopentane heptanoic or heptenoic acid, 2-arylalkyl or arylalkenyl and derivatives as therapeutic agents | ALLERGAN, INC. (US) | 1996-01-23 | — | — | US | disclosed |